Intradialytic hypotension (IDH) is defined as a reduction in
systolic blood pressure by more than 20 mm-Hg or a drop in mean arterial
pressure by 10 mmHg. It is associated with symptoms such as yawning, nausea, abdominal
discomfort, sighing, vomiting, restlessness, muscle cramps, dizziness or
fainting, and others. It affects patient well-being, restricts ultrafiltration,
and hikes the risk for coronary & cerebral ischemic events along with vascular
access thrombosis.
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Various research activities are conducted to determine
effects of IDH with several other conditions. Researchers at St. Luke's
International Hospital, Tokyo found that iron deficiency occurring in absence
of anemia is related to intradialytic hypotension. Kenichiro Koitabashi and
team carried out analysis of biochemical and clinical parameters of 99 patients
on maintenance hemodialysis. 44 out of 99 patients were diagnosed with IDH. In
these patients, transferrin saturation (TSAT) was found to be 18.1%. After the
analysis, it was found that a TSAT level below 20% increased the risk of IDH by
three-fold as compared with higher TSAT levels. “Given the effects of IDH on HD
patients, our study underscores the importance of treating iron deficiency even
without the presence of anemia,” the investigators concluded.
In another experiment, researchers at Fudan University,
Shanghai, China found that long-term risk of death can be predicted with the
help of IDH among patients on maintenance hemodialysis. A total of 117 of 293
patients were diagnosed with IDH, which researchers defined as a sudden drop in
systolic blood pressure of more than 20 mmHg or in mean arterial pressure of
more than 10 mmHg. Intradialytic blood pressure was monitored for a period of
three months. Five-year mortality rate was noted along with effects of IDH
incidence. It was observed that 84 patients died with mortality rate of 5.9%
per year. It was also observed that mortality rate increased with IDH
incidence. It was evident from the study that IDH increases long-term death
risk.
Researchers conducted a study to examine factors related to
IDH in hemodialysis patients and reduce the effects. Outcomes of the study were
studied for the period of 3 months. Investigators found that over 40% of the
patients had improvement in their blood pressure profile. It was observed that
minor changes in dialysis prescription can reduce the incidence of IDH in
patients on maintenance hemodialysis. To treat patients with frequent IDH, a
careful plan of action, limiting fluid & salt, taking right amount of dose
of prescription at the right time of the day, and conducting dialysis
treatments on time can reduce the risk of IDH significantly.
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Analysts studying the industry have presented a thorough
analysis on current market trends and future opportunities. Big Market Research
has added a report, titled, “Global Intra-Dialytic Hypotension (IDH) Market
Report 2016.” The report offers a comprehensive analysis of industry chain
structure, industry chain structure, prominent manufacturers, and supply &
sales status.
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